In the fabulous world of Mr. Fox (George Clooney), his anthropomorphic ways give him the control of the hen house and make him the bane of the local farmers. His criminal sprees are the stuff of legend by his wife Mrs. Fox (Meryl Streep) and son Ash (Jason Schwartzman) want him to go straight, but he has one last major heist in him in which he will take on Walter Boggis (Robin Hurlstone) who has the local chicken farm, Nathan Bunce (Hugo Guinness) who owns a pig farm, and Franklin Bean (Michael Gambon) who owns a turkey farm, a trio of unpleasant merchants. With his partner in crime Kylie the possum (Wally Wolodarksky), a major crime may be underway.